Search on:
1,25-DIHYDROXYVITAMIN D3
Descriptors Found:
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DeCS
Descriptor
English
:
Calcitriol
Descriptor
Spanish
:
Calcitriol
Descriptor
Portuguese
:
Calcitriol
Synonyms
English
:
1 alpha,25-Dihydroxycholecalciferol
1 alpha,25-Dihydroxyvitamin D3
1,25-Dihydroxycholecalciferol
1,25-Dihydroxyvitamin D3
Tree Number:
D04.808.247.222.159.478.387.300
D04.808.247.808.146.478.387.300
D04.808.812.768.196.478.387.300
D10.570.938.146.478.387.300
Definition
English
:
The physiologically active form of
vitamin D
. It is formed primarily in the
kidney
by enzymatic
hydroxylation
of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low
blood
calcium
levels and
parathyroid hormone
.
Calcitriol
increases
intestinal absorption
of
calcium
and
phosphorus
, and in concert with
parathyroid hormone
increases
bone resorption.
Indexing Annotation
English
:
deficiency: coordinate
CALCITRIOL
/defic (IM) with
VITAMIN D DEFICIENCY
(IM)
Pharmacological Action:
Bone Density Conservation Agents
Calcium Channel Agonists
Vitamins
See Related
English
:
Receptors, Calcitriol
History Note
English
:
82
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
2151
Unique Identifier:
D002117
Occurrence in VHL
:
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